Lysosomal hydrolases of the epidermis. I. Glycosidases.

TitleLysosomal hydrolases of the epidermis. I. Glycosidases.
Publication TypeJournal Article
Year of Publication1975
AuthorsMier PD, van den Hurk JJ
JournalBr J Dermatol
Date Published1975 Jul
KeywordsAcetylglucosaminidase, Animals, Galactosidases, Glycoside Hydrolases, Guinea Pigs, Hydrogen-Ion Concentration, Kinetics, Lysosomes, Skin

Seven distinct glycosidases (EC 3.2) have been characterized in guinea-pig epidermis. Their properties indicate them to be of lysosomal origin. The 'profile' of the epidermal glycosidases is significantly different from that reported for whole skin, the activities of beta-galactosidase and beta-acetylglucosaminidase being very high and those of the remaining enzymes relatively low in epidermis.

Alternate JournalBr. J. Dermatol.
PubMed ID30