@article {407,
	title = {Microbial nanowires: a new paradigm for biological electron transfer and bioelectronics.},
	journal = {ChemSusChem},
	volume = {5},
	year = {2012},
	month = {2012 Jun},
	pages = {1039-46},
	abstract = {<p>The discovery that Geobacter sulfurreducens can produce protein filaments with metallic-like conductivity, known as microbial nanowires, that facilitate long-range electron transport is a paradigm shift in biological electron transfer and has important implications for biogeochemistry, microbial ecology, and the emerging field of bioelectronics. Although filaments in a wide diversity of microorganisms have been called microbial nanowires, the type IV pili of G. sulfurreducens and G. metallireducens are the only filaments that have been shown to be required for extracellular electron transport to extracellular electron acceptors or for conduction of electrons through biofilms. Studies of G. sulfurreducens pili preparations and intact biofilms under physiologically relevant conditions have provided multiple lines of evidence for metallic-like conduction along the length of pili and for the possibility of pili networks to confer high conductivity within biofilms. This mechanism of electron conduction contrasts with the previously known mechanism for biological electron transfer via electron tunneling or hopping between closely associated molecules, a strategy unlikely to be well adapted for long-range electron transport outside the cell. In addition to promoting electron exchange with abiotic electron acceptors, microbial nanowires have recently been shown to be involved in direct interspecies electron transfer between syntrophic partners. An improved understanding of the mechanisms for metallic-like conductivity in microbial nanowires, as well as engineering microorganisms with desirable catalytic abilities with nanowires, could lead to new applications in microbial electrosynthesis and bioelectronics.</p>},
	keywords = {Bacterial Physiological Phenomena, Biofilms, Biotechnology, Electric Conductivity, Ferric Compounds, Fimbriae Proteins, Fimbriae, Bacterial, Nanostructures, Oxidation-Reduction},
	issn = {1864-564X},
	doi = {10.1002/cssc.201100733},
	author = {Malvankar, Nikhil S and Lovley, Derek R}
}
@article {415,
	title = {Geobacter: the microbe electric{\textquoteright}s physiology, ecology, and practical applications.},
	journal = {Adv Microb Physiol},
	volume = {59},
	year = {2011},
	month = {2011},
	pages = {1-100},
	abstract = {Geobacter species specialize in making electrical contacts with extracellular electron acceptors and other organisms. This permits Geobacter species to fill important niches in a diversity of anaerobic environments. Geobacter species appear to be the primary agents for coupling the oxidation of organic compounds to the reduction of insoluble Fe(III) and Mn(IV) oxides in many soils and sediments, a process of global biogeochemical significance. Some Geobacter species can anaerobically oxidize aromatic hydrocarbons and play an important role in aromatic hydrocarbon removal from contaminated aquifers. The ability of Geobacter species to reductively precipitate uranium and related contaminants has led to the development of bioremediation strategies for contaminated environments. Geobacter species produce higher current densities than any other known organism in microbial fuel cells and are common colonizers of electrodes harvesting electricity from organic wastes and aquatic sediments. Direct interspecies electron exchange between Geobacter species and syntrophic partners appears to be an important process in anaerobic wastewater digesters. Functional and comparative genomic studies have begun to reveal important aspects of Geobacter physiology and regulation, but much remains unexplored. Quantifying key gene transcripts and proteins of subsurface Geobacter communities has proven to be a powerful approach to diagnose the in situ physiological status of Geobacter species during groundwater bioremediation. The growth and activity of Geobacter species in the subsurface and their biogeochemical impact under different environmental conditions can be predicted with a systems biology approach in which genome-scale metabolic models are coupled with appropriate physical/chemical models. The proficiency of Geobacter species in transferring electrons to insoluble minerals, electrodes, and possibly other microorganisms can be attributed to their unique "microbial nanowires," pili that conduct electrons along their length with metallic-like conductivity. Surprisingly, the abundant c-type cytochromes of Geobacter species do not contribute to this long-range electron transport, but cytochromes are important for making the terminal electrical connections with Fe(III) oxides and electrodes and also function as capacitors, storing charge to permit continued respiration when extracellular electron acceptors are temporarily unavailable. The high conductivity of Geobacter pili and biofilms and the ability of biofilms to function as supercapacitors are novel properties that might contribute to the field of bioelectronics. The study of Geobacter species has revealed a remarkable number of microbial physiological properties that had not previously been described in any microorganism. Further investigation of these environmentally relevant and physiologically unique organisms is warranted.},
	keywords = {Biotechnology, Ecology, Environmental Remediation, Ferric Compounds, Geobacter},
	issn = {0065-2911},
	doi = {10.1016/B978-0-12-387661-4.00004-5},
	author = {Lovley, Derek R and Ueki, Toshiyuki and Zhang, Tian and Malvankar, Nikhil S and Shrestha, Pravin M and Flanagan, Kelly A and Aklujkar, Muktak and Butler, Jessica E and Giloteaux, Ludovic and Rotaru, Amelia-Elena and Holmes, Dawn E and Franks, Ashley E and Orellana, Roberto and Risso, Carla and Nevin, Kelly P}
}
@article {731,
	title = {Biotechnological potential of aquatic plant-microbe interactions.},
	journal = {Curr Opin Biotechnol},
	volume = {21},
	year = {2010},
	month = {2010 Jun},
	pages = {339-45},
	abstract = {The rhizosphere in terrestrial systems is the region of soil surrounding plant roots where there is increased microbial activity; in aquatic plants, this definition may be less clear because of diffusion of nutrients in water, but there is still a zone of influence by plant roots in this environment [1]. Within that zone chemical conditions differ from those of the surrounding environment as a consequence of a range of processes that were induced either directly by the activity of plant roots or by the activity of rhizosphere microflora. Recently, there are a number of new studies related to rhizospheres of aquatic plants and specifically their increased potential for remediation of contaminants, especially remediation of metals through aquatic plant-microbial interaction.},
	keywords = {Biodegradation, Environmental, Biotechnology, Hydrogen-Ion Concentration, Plant Roots, Plants},
	issn = {1879-0429},
	doi = {10.1016/j.copbio.2010.04.004},
	author = {Stout, L and N{\"u}sslein, K}
}
@article {465,
	title = {Future shock from the microbe electric.},
	journal = {Microb Biotechnol},
	volume = {2},
	year = {2009},
	month = {2009 Mar},
	pages = {139-41},
	keywords = {Bacteria, Bioelectric Energy Sources, Biotechnology, Electricity, Energy-Generating Resources},
	issn = {1751-7915},
	doi = {10.1111/j.1751-7915.2009.00090_9.x},
	author = {Lovley, Derek R}
}
@article {535,
	title = {Extracellular electron transfer via microbial nanowires.},
	journal = {Nature},
	volume = {435},
	year = {2005},
	month = {2005 Jun 23},
	pages = {1098-101},
	abstract = {Microbes that can transfer electrons to extracellular electron acceptors, such as Fe(iii) oxides, are important in organic matter degradation and nutrient cycling in soils and sediments. Previous investigations on electron transfer to Fe(iii) have focused on the role of outer-membrane c-type cytochromes. However, some Fe(iii) reducers lack c-cytochromes. Geobacter species, which are the predominant Fe(iii) reducers in many environments, must directly contact Fe(iii) oxides to reduce them, and produce monolateral pili that were proposed, on the basis of the role of pili in other organisms, to aid in establishing contact with the Fe(iii) oxides. Here we report that a pilus-deficient mutant of Geobacter sulfurreducens could not reduce Fe(iii) oxides but could attach to them. Conducting-probe atomic force microscopy revealed that the pili were highly conductive. These results indicate that the pili of G. sulfurreducens might serve as biological nanowires, transferring electrons from the cell surface to the surface of Fe(iii) oxides. Electron transfer through pili indicates possibilities for other unique cell-surface and cell-cell interactions, and for bioengineering of novel conductive materials.},
	keywords = {Biotechnology, Electric Conductivity, Electron Transport, Ferric Compounds, Fimbriae Proteins, Fimbriae, Bacterial, Genes, Bacterial, Geobacter, Microscopy, Atomic Force, Microscopy, Electron, Transmission, Mutation, Nanostructures, Phylogeny},
	issn = {1476-4687},
	doi = {10.1038/nature03661},
	author = {Reguera, Gemma and McCarthy, Kevin D and Mehta, Teena and Nicoll, Julie S and Tuominen, Mark T and Lovley, Derek R}
}
@article {580,
	title = {Harnessing microbially generated power on the seafloor.},
	journal = {Nat Biotechnol},
	volume = {20},
	year = {2002},
	month = {2002 Aug},
	pages = {821-5},
	abstract = {In many marine environments, a voltage gradient exists across the water sediment interface resulting from sedimentary microbial activity. Here we show that a fuel cell consisting of an anode embedded in marine sediment and a cathode in overlying seawater can use this voltage gradient to generate electrical power in situ. Fuel cells of this design generated sustained power in a boat basin carved into a salt marsh near Tuckerton, New Jersey, and in the Yaquina Bay Estuary near Newport, Oregon. Retrieval and analysis of the Tuckerton fuel cell indicates that power generation results from at least two anode reactions: oxidation of sediment sulfide (a by-product of microbial oxidation of sedimentary organic carbon) and oxidation of sedimentary organic carbon catalyzed by microorganisms colonizing the anode. These results demonstrate in real marine environments a new form of power generation that uses an immense, renewable energy reservoir (sedimentary organic carbon) and has near-immediate application.},
	keywords = {Bacteria, Bioelectric Energy Sources, Biotechnology, Carbon, Conservation of Energy Resources, DNA, Ribosomal, Electricity, Electrodes, Environmental Microbiology, Geologic Sediments, Molecular Sequence Data, New Jersey, Oceans and Seas, Oregon, Oxidation-Reduction, RNA, Bacterial, RNA, Ribosomal, 16S, Sulfides},
	issn = {1087-0156},
	doi = {10.1038/nbt716},
	author = {Tender, Leonard M and Reimers, Clare E and Stecher, Hilmar A and Holmes, Dawn E and Bond, Daniel R and Lowy, Daniel A and Pilobello, Kanoelani and Fertig, Stephanie J and Lovley, Derek R}
}
@article {596,
	title = {Microbial detoxification of metals and radionuclides.},
	journal = {Curr Opin Biotechnol},
	volume = {12},
	year = {2001},
	month = {2001 Jun},
	pages = {248-53},
	abstract = {Microorganisms have important roles in the biogeochemical cycling of toxic metals and radionuclides. Recent advances have been made in understanding metal-microbe interactions and new applications of these processes to the detoxification of metal and radionuclide contamination have been developed.},
	keywords = {Bacteria, Biodegradation, Environmental, Biotechnology, Environmental Pollution, Genetic Engineering, Geologic Sediments, Metals, Heavy, Radioisotopes},
	issn = {0958-1669},
	author = {Lloyd, J R and Lovley, D R}
}
@article {629,
	title = {Bioremediation of metal contamination.},
	journal = {Curr Opin Biotechnol},
	volume = {8},
	year = {1997},
	month = {1997 Jun},
	pages = {285-9},
	abstract = {Recent studies have demonstrated that microbes might be used to remediate metal contamination by removing metals from contaminated water or waste streams, sequestering metals in soils and sediments or solubilizing metals to aid in their extraction. This is primarily accomplished either by biosorption of metals or enzymatically catalyzed changes in the metal redox state. Bioremediation of metals is still primarily a research problem with little large-scale application of this technology.},
	keywords = {Adsorption, Bacteria, Biomass, Biotechnology, Environmental Pollutants, Metals, Oxidation-Reduction},
	issn = {0958-1669},
	author = {Lovley, D R and Coates, J D}
}
