@article {1443,
	title = {Mycobacterial lipid logic.},
	journal = {Cell Host Microbe},
	volume = {15},
	year = {2014},
	month = {2014 Jan 15},
	pages = {1-2},
	abstract = {<p>During infection of the lung epithelium, Mycobacterium tuberculosis must infect and survive within macrophages long enough to be transported into deeper lung tissues. Cambier et~al. (2013) show that pathogenic mycobacteria use the coordinated action of two cell wall glycolipids to regulate macrophage recruitment to initial infection sites.</p>},
	keywords = {Animals, Female, Immune Evasion, Macrophages, Membrane Lipids, Mycobacterium},
	issn = {1934-6069},
	doi = {10.1016/j.chom.2013.12.005},
	author = {Siegrist, M Sloan and Bertozzi, Carolyn R}
}
@article {1447,
	title = {Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition.},
	journal = {Proc Natl Acad Sci U S A},
	volume = {106},
	year = {2009},
	month = {2009 Nov 3},
	pages = {18792-7},
	abstract = {<p>The Esx secretion pathway is conserved across Gram-positive bacteria. Esx-1, the best-characterized system, is required for virulence of Mycobacterium tuberculosis, although its precise function during infection remains unclear. Esx-3, a paralogous system present in all mycobacterial species, is required for growth in vitro. Here, we demonstrate that mycobacteria lacking Esx-3 are defective in acquiring iron. To compete for the limited iron available in the host and the environment, these organisms use mycobactin, high-affinity iron-binding molecules. In the absence of Esx-3, mycobacteria synthesize mycobactin but are unable to use the bound iron and are impaired severely for growth during macrophage infection. Mycobacteria thus require a specialized secretion system for acquiring iron from siderophores.</p>},
	keywords = {Animals, Bacterial Proteins, Genome, Bacterial, Iron, Macrophages, Mice, Mutation, Mycobacterium, Mycobacterium Infections, Oxazoles, Protein Binding, Secretory Pathway, Siderophores, Transcription, Genetic, Up-Regulation},
	issn = {1091-6490},
	doi = {10.1073/pnas.0900589106},
	author = {Siegrist, M Sloan and Unnikrishnan, Meera and McConnell, Matthew J and Borowsky, Mark and Cheng, Tan-Yun and Siddiqi, Noman and Fortune, Sarah M and Moody, D Branch and Rubin, Eric J}
}
